The aim of this paper was to present the essence of the relocation process of companies with particular consideration of intra-national migration. The author arranged definitions and presented factors of the relocation of companies. The paper ends with case studies of the companies that entirely or partly relocated their business activity in the country. The information on migration was obtained on the basis of the conducted survey among randomly selected enterprises. Further information was collected from web pages of surveyed entities and press releases. As a result of the conducted analysis the conclusions were drawn towards the surveyed enterprises. It was observed that domestic relocation concerns both small and large enterprises dealing with manufacturing, providing services and trading. Internal migration may be conducted entirely or partly. Companies may transfer their seats or branches. The main reason for a change of localization is insufficient supply of manufacturing area. The conducted research reflect only fragment of the process of domestic relocation in order to draw the overall conclusions in this respect is indispensable to make extension at the bigger scale of enterprises.